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64 channel optrode  (NeuroNexus Technologies)


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    NeuroNexus Technologies 64 channel optrode
    Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. <t>The</t> <t>64-channel</t> optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
    64 Channel Optrode, supplied by NeuroNexus Technologies, used in various techniques. Bioz Stars score: 94/100, based on 373 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/optrode/bio_rxiv__64898__2026__03__23__713540-45-1-4?v=NeuroNexus+Technologies
    Average 94 stars, based on 373 article reviews
    64 channel optrode - by Bioz Stars, 2026-07
    94/100 stars

    Images

    1) Product Images from "Cell-Type-Specific Bidirectional Modulation of the Cortico–Thalamo–Cortical Sensory Pathway by Transcranial Focused Ultrasound (tFUS)"

    Article Title: Cell-Type-Specific Bidirectional Modulation of the Cortico–Thalamo–Cortical Sensory Pathway by Transcranial Focused Ultrasound (tFUS)

    Journal: bioRxiv

    doi: 10.64898/2026.03.23.713540

    Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. The 64-channel optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).
    Figure Legend Snippet: Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. The 64-channel optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).

    Techniques Used: Sonication, Ex Vivo



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    Image Search Results


    Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. The 64-channel optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).

    Journal: bioRxiv

    Article Title: Cell-Type-Specific Bidirectional Modulation of the Cortico–Thalamo–Cortical Sensory Pathway by Transcranial Focused Ultrasound (tFUS)

    doi: 10.64898/2026.03.23.713540

    Figure Lengend Snippet: Experimental setup and ultrasound parameter. (A) Experimental setup of intracranial electrodes for recording multi-region signals, optical fiber for activating specific type of neurons and 128-element random array ultrasound transducer. The 64-channel optrode was inserted into left somatosensory cortex (S1) and 32-channel electrode was inserted into left posteromedial of the thalamus (POm). Vibration-tactile stimulation was applied to the right hind paw. (B) Ultrasound parameters used in this study. The inter-sonication interval (ISI) was set at 2.5s with 10% jitter to avoid neuronal adaptation to fixed ISI. Ultrasound duration (UD) was set at 100ms with vibration stimulation or 67ms for tFUS only. Pulse repetitive frequencies (PRFs) and duty cycles (DCs) tested in this study were 30Hz with 0.6%DC and 3000Hz with 60% DC. Pulse durations (PD) were calculated by PRF*DCs. (C-D) Ex-vivo hydrophone peak-to-peak pressure amplitude z-axis (upper) and y-axis (bottom) scan at the estimated targeted brain region with low pressure (C, ∼98kPa) and high pressure (D, ∼163kPa).

    Article Snippet: A 64-channel Optrode (A1×64-Edge-6mm-22.5-177-OXA64LP, Neuronexus, Ann Arbor, MI, USA) was inserted into S1 from the left side (angle: 40°) to make sure the signals were recorded from the virus injection site.

    Techniques: Sonication, Ex Vivo